Title : Hinokitiol, a tropolone derivative, inhibits mouse melanoma (B16-F10) cell migration and in vivo tumor formation.

Pub. Date : 2015 Jan 5

PMID : 25449038






1 Functional Relationships(s)
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1 Hinokitiol appeared to achieve this effect by reducing the expression of MMP-1 and by suppressing the phosphorylation of mitogen- activated protein kinase (MAPK) signaling molecules such as extracellular signal-regulated kinase (ERK) 1/2, p38 MAPK and c-Jun N-terminal kinases (JNK). beta-thujaplicin mitogen-activated protein kinase 1 Mus musculus