Title : Pifithrin-alpha has a p53-independent cytoprotective effect on docosahexaenoic acid-induced cytotoxicity in human hepatocellular carcinoma HepG2 cells.

Pub. Date : 2015 Jan 22

PMID : 25448278






1 Functional Relationships(s)
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1 PFT significantly abrogated DHA-induced cytotoxicity in wild-type HepG2 cells (normal expression of p53) and after p53-knockdown by siRNA, as well as in Hep3B (p53 null) and Huh7 (p53 mutant) cells. Docosahexaenoic Acids tumor protein p53 Homo sapiens