Pub. Date : 2015 Jan-Mar
PMID : 25447342
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 20-HETE and its metabolite produced by ADH activity, 20-carboxy-arachidonic acid, protected the glomerular permeability barrier against an ADH inhibitor, puromycin or FSGS permeability factor. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | aldo-keto reductase family 1, member A1 (aldehyde reductase) | Mus musculus |
| 2 | 20-HETE and its metabolite produced by ADH activity, 20-carboxy-arachidonic acid, protected the glomerular permeability barrier against an ADH inhibitor, puromycin or FSGS permeability factor. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | aldo-keto reductase family 1, member A1 (aldehyde reductase) | Mus musculus |
| 3 | We conclude that ADH activity is required for glomerular function, 20-HETE is a physiological substrate of ADH in podocytes and that podocytes are useful biosensors to understand glomeruloprotective effects of ethanol. | 20-hydroxy-5,8,11,14-eicosatetraenoic acid | aldo-keto reductase family 1, member A1 (aldehyde reductase) | Mus musculus |