Title : Arsenic trioxide amplifies cisplatin toxicity in human tubular cells transformed by HPV-16 E6/E7 for further therapeutic directions in renal cell carcinoma.

Pub. Date : 2015 Jan 28

PMID : 25444910






1 Functional Relationships(s)
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1 By contrast, arsenic trioxide, which by inhibiting wild-type p53-induced phosphatase-1 that serves responses downstream of p53, and by depolymerizing tubulin, synergistically enhanced cisplatin cytotoxicity including loss of SP cells. Arsenic Trioxide tumor protein p53 Homo sapiens