Title : CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways.

Pub. Date : 2015 Oct

PMID : 25428830






1 Functional Relationships(s)
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1 Through our anti-osteoclastogenic compound screening experiments we encountered a modified version of the Cathepsin B inhibitor CA-074: the cell membrane-permeable CA-074Me (L-3-trans-(Propylcarbamoyl) oxirane-2-carbonyl]-L-isoleucyl-L-proline Methyl Ester). N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline cathepsin B Mus musculus