Title : Targeting ornithine decarboxylase reverses the LIN28/Let-7 axis and inhibits glycolytic metabolism in neuroblastoma.

Pub. Date : 2015 Jan 1

PMID : 25415050






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This is the first study to demonstrate that DFMO treatment restores balance to the LIN28/Let-7 axis and inhibits glycolytic metabolism and neurosphere formation in NB and that PET scans may be a meaningful imaging tool to evaluate the therapeutic effects of DFMO treatment. Eflornithine lin-28 homolog A Homo sapiens