Title : Regulatory role of autophagy in globular adiponectin-induced apoptosis in cancer cells.

Pub. Date : 2014 Sep

PMID : 25414767






2 Functional Relationships(s)
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1 Interestingly, gene silencing of LC3B, an autophagy marker, significantly enhanced gAcrp-induced apoptosis in both HepG2 and MCF-7 cell lines, whereas induction of autophagy by rapamycin, an mTOR inhibitor, significantly prevented gAcrp-induced apoptosis in hepatoma cells HepG2. gacrp microtubule associated protein 1 light chain 3 beta Homo sapiens
2 Interestingly, gene silencing of LC3B, an autophagy marker, significantly enhanced gAcrp-induced apoptosis in both HepG2 and MCF-7 cell lines, whereas induction of autophagy by rapamycin, an mTOR inhibitor, significantly prevented gAcrp-induced apoptosis in hepatoma cells HepG2. gacrp microtubule associated protein 1 light chain 3 beta Homo sapiens