Title : The effect of dolutegravir on the pharmacokinetics of metformin in healthy subjects.

Pub. Date : 2014

PMID : 25394090






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In vitro, DTG inhibits organic cation transporter 2 (OCT2) and multidrug and toxin extrusion transporter 1 (MATE 1) which are known to be involved in the disposition of metformin. Metformin solute carrier family 22 member 2 Homo sapiens
2 In vitro, DTG inhibits organic cation transporter 2 (OCT2) and multidrug and toxin extrusion transporter 1 (MATE 1) which are known to be involved in the disposition of metformin. Metformin solute carrier family 22 member 2 Homo sapiens