Title : Zoledronic acid induces apoptosis and S-phase arrest in mesothelioma through inhibiting Rab family proteins and topoisomerase II actions.

Pub. Date : 2014 Nov 13

PMID : 25393473






1 Functional Relationships(s)
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1 ZOL-treated cells decreased a ratio of membrane to cytoplasmic fractions in RhoA, Cdc42 and Rab6 but less significantly Rac1 proteins, indicating that these proteins were possible targets for ZOL-induced actions. Zoledronic Acid Rac family small GTPase 1 Homo sapiens