Title : Effects of silica exposure on the cardiac and renal inflammatory and fibrotic response and the antagonistic role of interleukin-1 beta in C57BL/6 mice.

Pub. Date : 2016 Feb

PMID : 25388157






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This study tried to investigate the silica-induced inflammatory and fibrotic changes in the heart and kidney and evaluate the role of interleukin (IL)-1 beta (beta) in silica-induced cardiac and renal damage. Silicon Dioxide interleukin 1 beta Mus musculus
2 Further studies showed that usage of anti-IL-1beta mAb decreased the inflammatory response of the heart and kidney induced by inhalational silica and also attenuated fibrosis in the mouse kidney. Silicon Dioxide interleukin 1 beta Mus musculus
3 Neutralisation of IL-1beta attenuated the silica-induced inflammatory response of the heart and kidney and decreased fibrosis in the mouse kidney. Silicon Dioxide interleukin 1 beta Mus musculus