Pub. Date : 2014
PMID : 25374032
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Galpha also interacts with GIRK channels and since PTX-sensitive Galpha subunits show higher affinity of interaction they confer signaling specificity to G Protein- Coupled Receptors (GPCRs) that normally couple to these G protein subunits. | ptx | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |
| 2 | In heterologous systems, overexpression of non PTX-sensitive Galpha subunits scavenges the available Gbetagamma and biases GIRK activation through GPCRs that couple to these Galpha subunits. | ptx | potassium inwardly rectifying channel subfamily J member 3 L homeolog | Xenopus laevis |