Title : Effects of arsenic compounds on growth, cell-cycle distribution and apoptosis of tretinoin-resistant human promyelocytic leukemia cells.

Pub. Date : 2014 Nov

PMID : 25368250






3 Functional Relationships(s)
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1 RESULTS: The 50% inhibitory concentrations (IC50 values) for As2O3 against proliferation of HL-60 and HL-60-R2 cells were 12.2 and 7.2 muM, while those for arsenate were >200 and 62.1 muM, respectively. Arsenic Trioxide latexin Homo sapiens
2 RESULTS: The 50% inhibitory concentrations (IC50 values) for As2O3 against proliferation of HL-60 and HL-60-R2 cells were 12.2 and 7.2 muM, while those for arsenate were >200 and 62.1 muM, respectively. Arsenic Trioxide latexin Homo sapiens
3 As2O3 and arsenate increased the proportion of apoptotic cells dose-dependently at a concentration range of 5-200 muM. Arsenic Trioxide latexin Homo sapiens