Title : Differential impact of bortezomib on HL-60 and K562 cells.

Pub. Date : 2015 Jan

PMID : 25367763






2 Functional Relationships(s)
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1 The relative resistance of K562 cells to bortezomib correlated well with significantly higher expression of HSP27, HSP70, HSP90alpha, HSP90beta and GRP75 in these cells. Bortezomib heat shock protein 90 alpha family class A member 1 Homo sapiens
2 Incubation of both HL-60 and K562 cells with bortezomib induced a cleavage of HSP90beta as well as expression of HSP70 and HSP90beta but bortezomib did not affect levels of HSP27, HSP90alpha, GRP75 and GRP78. Bortezomib heat shock protein 90 alpha family class A member 1 Homo sapiens