Title : Lipopolysaccharide-induced gene expression in murine peritoneal macrophages is selectively suppressed by agents that elevate intracellular cAMP.

Pub. Date : 1989 Feb 15

PMID : 2536771






1 Functional Relationships(s)
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1 If macrophages are first treated with cholera toxin or dibutyryl cAMP 15 min before stimulation with LPS, the accumulation of mRNA encoding both JE and TNF is strongly suppressed whereas mRNA levels for KC and IL-1 are unaffected. Cyclic AMP interleukin 1 complex Mus musculus