Pub. Date : 2015 Jun 1
PMID : 25359574
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ATF2 contributes to cisplatin resistance in non-small cell lung cancer and celastrol induces cisplatin resensitization through inhibition of JNK/ATF2 pathway. | celastrol | activating transcription factor 2 | Homo sapiens |
| 2 | Celastrol-mediated ATF2/cJUN activity was measured. | celastrol | activating transcription factor 2 | Homo sapiens |
| 3 | By contrast, Celastrol-mediated ATF2/cJUN functional inhibition restored the response to CDDP. | celastrol | activating transcription factor 2 | Homo sapiens |
| 4 | Altogether, our results indicate a potential increase in CDDP sensitivity, on Celastrol-mediated ATF2/cJUN inhibition. | celastrol | activating transcription factor 2 | Homo sapiens |