Title : 13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppression.

Pub. Date : 2014 Oct 23

PMID : 25342459






1 Functional Relationships(s)
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1 13-AC-induced apoptosis was confirmed through observation of a change in DeltaPsim, up-regulated expression levels of Bax and Bad proteins, down-regulated expression levels of Bcl-2, Bcl-xl and Mcl-1 proteins, and the activation of caspase-3, caspase-9, p38 and JNK. 13-acetoxysarcocrassolide caspase 3 Homo sapiens