Title : Growth arrest and apoptosis via caspase activation of dioscoreanone in human non-small-cell lung cancer A549 cells.

Pub. Date : 2014 Oct 24

PMID : 25342427






1 Functional Relationships(s)
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1 Moreover, the highest activity of caspase-3 in DN-treated A549 cells was detected within the first 24 h, and pretreatment with the general caspase inhibitor z-VAD-fmk completely abolished such activity and also DN-induced apoptosis in a dose-dependent manner. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 3 Homo sapiens