Title : Ethanol Mediates Cell Cycle Arrest and Apoptosis in SK-N-SH Neuroblastoma Cells.

Pub. Date : 2014 Mar

PMID : 25337571






3 Functional Relationships(s)
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1 Ethanol also increased the phosphorylation of p53 and p53 activation was followed by an increase in the p21 tumor suppressor protein accompanied by a gradual decrease in phospho-Rb protein. Ethanol tumor protein p53 Homo sapiens
2 Ethanol also increased the phosphorylation of p53 and p53 activation was followed by an increase in the p21 tumor suppressor protein accompanied by a gradual decrease in phospho-Rb protein. Ethanol tumor protein p53 Homo sapiens
3 CONCLUSION: Our results suggest that ethanol mediates apoptosis of neuroblastoma cells by stimulating p53-related cell cycle arrest mediated through activation of the JNK-related pathway. Ethanol tumor protein p53 Homo sapiens