Pub. Date : 2014 Oct 14
PMID : 25315241
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin inhibits breast cancer stem cell migration by amplifying the E-cadherin/beta-catenin negative feedback loop. | Curcumin | cadherin 1 | Homo sapiens |
| 2 | RESULTS: Here, we report that bCSCs are endowed with aggravated migration property due to the inherent suppression of the tumor suppressor, E-cadherin, which is restored by curcumin. | Curcumin | cadherin 1 | Homo sapiens |
| 3 | CONCLUSIONS: Cumulatively, our findings disclose that curcumin inhibits bCSC migration by amplifying E-cadherin/beta-catenin negative feedback loop. | Curcumin | cadherin 1 | Homo sapiens |