Pub. Date : 2016 Jun
PMID : 25315214
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Tacrolimus suppressed the expression of MDC, IP-10, I-309, GRO-alpha, and TNF-alpha in LPS-stimulated THP-1 cells in a dose- and time-dependent manner. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 2 | CONCLUSION: Tacrolimus suppressed LPS-induced MDC, I-309, IP-10, GRO-alpha, and TNF-alpha expressions in monocytes through the MAPK-ERK pathway; thus, tacrolimus may yield therapeutic efficacy by modulating AD-associated cytokines and chemokines. | Tacrolimus | tumor necrosis factor | Homo sapiens |
| 3 | CONCLUSION: Tacrolimus suppressed LPS-induced MDC, I-309, IP-10, GRO-alpha, and TNF-alpha expressions in monocytes through the MAPK-ERK pathway; thus, tacrolimus may yield therapeutic efficacy by modulating AD-associated cytokines and chemokines. | Tacrolimus | tumor necrosis factor | Homo sapiens |