Title : A novel series of di-fluorinated propanedione derivatives synergistically augment paclitaxel mediated caspase 3 activation in ovarian cancer cells.

Pub. Date : 2014 Jul-Sep

PMID : 25313764






1 Functional Relationships(s)
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1 RESULTS: Both nitro/methoxy (Group I) and halogen substituted propandiones at ortho, meta and para positions (Group II) showed a moderate increase in caspase-3 activity by 1.5- to 3.3-fold as compared with controls. Halogens caspase 3 Homo sapiens