Title : The hyperglycemic byproduct methylglyoxal impairs anticoagulant activity through covalent adduction of antithrombin III.

Pub. Date : 2014 Dec

PMID : 25307422






1 Functional Relationships(s)
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1 Results from LC-MS/MS experiments revealed that MGO covalently adducts the active site Arg 393 of ATIII through two distinct glyoxalation mechanisms. Arginine serpin family C member 1 Homo sapiens