Title : Effects of a glycine transporter-1 inhibitor and D-serine on MK-801-induced immobility in the forced swimming test in rats.

Pub. Date : 2015 Feb 1

PMID : 25300471






1 Functional Relationships(s)
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1 The present results show that the stimulation of the NMDA receptor through the glycine site on the receptor either directly with D-serine or by blocking glycine transporter-1 attenuates the immobility elicited by the subchronic administration of MK-801 and may be potentially useful for the treatment of negative symptoms of schizophrenia. Glycine solute carrier family 6 member 9 Rattus norvegicus