Title : Natriuretic and diuretic effects of infusion of atrial natriuretic factor in conscious dogs.

Pub. Date : 1989 Oct

PMID : 2529778






2 Functional Relationships(s)
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1 During the 0.01-micrograms.kg-1.min-1 infusion, the plasma concentration of ANF rose approximately threefold (from 68 +/- 7 to 207 +/- 14 pg/ml), with no change in urine flow rate, sodium excretion, or arterial pressure. Sodium natriuretic peptide A Canis lupus familiaris
2 At the highest dose of ANF (0.3 micrograms.kg-1.min-1) urine flow rose by 0.62 +/- 0.16 ml/min, P less than 0.05, and sodium excretion rose by 139 +/- 30 mu eq/min, P less than 0.05, whereas plasma levels of ANF rose to 2,436 +/- 320 pg/ml. Sodium natriuretic peptide A Canis lupus familiaris