Title : The induction of C/EBPβ contributes to vitamin D inhibition of ADAM17 expression and parathyroid hyperplasia in kidney disease.

Pub. Date : 2015 Mar

PMID : 25294851






1 Functional Relationships(s)
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1 Importantly, in rat SHPT, the correction of vitamin D deficiency effectively reversed the resistance to paricalcitol induction of C/EBPbeta to suppress ADAM17 expression and PTG enlargement, reducing PTH by 50%. paricalcitol ADAM metallopeptidase domain 17 Rattus norvegicus