Pub. Date : 2014 Oct 3
PMID : 25279700
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. | Sphingolipids | serine/threonine protein kinase YPK1 | Saccharomyces cerevisiae S288C |
| 2 | Ypk1, among other actions, alleviates negative regulation of L-serine:palmitoyl-CoA acyltransferase, upregulating production of long-chain base precursors to sphingolipids. | Sphingolipids | serine/threonine protein kinase YPK1 | Saccharomyces cerevisiae S288C |
| 3 | Ypk1-dependent phosphorylation of both proteins increased upon either sphingolipid depletion or heat shock and was important for cell survival. | Sphingolipids | serine/threonine protein kinase YPK1 | Saccharomyces cerevisiae S288C |