Title : Astrocytes mediate HIV-1 Tat-induced neuronal damage via ligand-gated ion channel P2X7R.

Pub. Date : 2015 Feb

PMID : 25272052






1 Functional Relationships(s)
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1 P2X7R antagonists, such as the oxidized ATP, A438079, brilliant blue G, and broad spectrum P2 receptor antagonist suramin, attenuated Tat-induced CCL2 release in a calcium- and extracellular signal-regulated kinase (ERK)1/2-dependent manner. Adenosine Triphosphate C-C motif chemokine ligand 2 Homo sapiens