Title : Structure-activity analysis of a CFTR channel potentiator: Distinct molecular parts underlie dual gating effects.

Pub. Date : 2014 Oct

PMID : 25267914






1 Functional Relationships(s)
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1 The practical utility of 5-nitro-2-(3-phenylpropylamino)benzoate (NPPB), one of the most efficacious potentiators of DeltaF508 CFTR identified to date, is limited by its pore-blocking side effect. 5-nitro-2-(3-phenylpropylamino)benzoic acid CF transmembrane conductance regulator Homo sapiens