Pub. Date : 2014 Dec 10
PMID : 25261710
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. | Lopinavir | PGP | Canis lupus familiaris |
2 | Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. | Lopinavir | PGP | Canis lupus familiaris |
3 | Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. | Lopinavir | PGP | Canis lupus familiaris |
4 | Oral absorption of lopinavir (LPV) is limited due to P-glycoprotein (P-gp) and multidrug resistance-associated protein2 (MRP2) mediated efflux by intestinal epithelial cells. | Lopinavir | PGP | Canis lupus familiaris |
5 | In the present study, dipeptide prodrug approach was employed to circumvent efflux pumps (P-gp and MRP2) and CYP3A4 mediated metabolism of LPV. | Lopinavir | PGP | Canis lupus familiaris |