Pub. Date : 2014 Oct 10
PMID : 25256746
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We assessed whether 5"-AMP-activated protein kinase (AMPK) in skeletal muscle is involved in the effect of SAL on glucose homeostasis. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 2 | Intracellular concentrations of SAL increased rapidly (<5 min) in both skeletal muscles, and the Thr(172) phosphorylation of the alpha subunit of AMPK increased in a dose- and time-dependent manner. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |
| 3 | These results suggest that SAL may be transported into skeletal muscle and may stimulate AMPK and glucose transport via energy deprivation in multiple muscle types. | Salicylates | protein kinase AMP-activated catalytic subunit alpha 2 | Rattus norvegicus |