Title : Structural insights into carbonic anhydrase IX isoform specificity of carbohydrate-based sulfamates.

Pub. Date : 2014 Oct 23

PMID : 25254302






1 Functional Relationships(s)
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1 Seven compounds inhibited CA IX with low nM Ki values of 1-2 nM and also exhibited permeability profiles to preferentially target the binding of extracellular CA IX over cytosolic CAs. Calcium carbonic anhydrase 9 Homo sapiens