Title : Increased spinal cord Na⁺-K⁺-2Cl⁻ cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain.

Pub. Date : 2014 Nov 7

PMID : 25253692






2 Functional Relationships(s)
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1 Inhibition of NKCC1 with bumetanide reversed the paclitaxel effect on GABA-mediated hyperpolarization and GABA reversal potentials. gamma-Aminobutyric Acid solute carrier family 12 member 2 Rattus norvegicus
2 Inhibition of NKCC1 with bumetanide reversed the paclitaxel effect on GABA-mediated hyperpolarization and GABA reversal potentials. gamma-Aminobutyric Acid solute carrier family 12 member 2 Rattus norvegicus