Title : Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.

Pub. Date : 2015 Jan

PMID : 25251602






1 Functional Relationships(s)
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1 Notably, lactate level was lower in MT-IDH2 cells which produced more 2-HG than MT-IDH1 cells, indicating that the Warburg effects can be overridden by the production of 2-HG. Lactic Acid isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens