Title : All-trans-retinoic acid and CD38 ligation differentially regulate CD1d expression and α-galactosylceramide-induced immune responses.

Pub. Date : 2015 Jan

PMID : 25248321






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 All-trans-retinoic acid (RA) and CD38, which is itself a target of RA, both independently regulate the differentiation of antigen presenting cells. Tretinoin CD38 molecule Homo sapiens
2 Whereas a physiological concentration (20 nM) of RA alone rapidly and markedly increased CD1d protein in THP-1 cells, there was a marked synergy between RA and ligation of CD38 with antibody to CD38. Tretinoin CD38 molecule Homo sapiens
3 Whereas a physiological concentration (20 nM) of RA alone rapidly and markedly increased CD1d protein in THP-1 cells, there was a marked synergy between RA and ligation of CD38 with antibody to CD38. Tretinoin CD38 molecule Homo sapiens