Pub. Date : 2015 Apr
PMID : 25231394
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Spermidine/spermine N (1)-acetyltransferase (SSAT) is a catabolic regulator of polyamines, ubiquitous molecules essential for cell proliferation and differentiation. | Polyamines | spermidine/spermine N1-acetyl transferase 1 | Mus musculus |
| 2 | The polyamine pattern in osteoblasts of SSAT mice was distorted in comparison with wild-type mice. | Polyamines | spermidine/spermine N1-acetyl transferase 1 | Mus musculus |
| 3 | However, treatment of osteoblasts with a SSAT-inducing functional polyamine analogue suggested that defective osteoblastogenesis resulted rather from other consequences of enhanced SSAT activity than lowered levels of the higher polyamines. | Polyamines | spermidine/spermine N1-acetyl transferase 1 | Mus musculus |
| 4 | However, treatment of osteoblasts with a SSAT-inducing functional polyamine analogue suggested that defective osteoblastogenesis resulted rather from other consequences of enhanced SSAT activity than lowered levels of the higher polyamines. | Polyamines | spermidine/spermine N1-acetyl transferase 1 | Mus musculus |
| 5 | However, treatment of osteoblasts with a SSAT-inducing functional polyamine analogue suggested that defective osteoblastogenesis resulted rather from other consequences of enhanced SSAT activity than lowered levels of the higher polyamines. | Polyamines | spermidine/spermine N1-acetyl transferase 1 | Mus musculus |