Pub. Date : 2014 Nov
PMID : 25230301
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Carboplatin-induced severe hypersensitivity reaction: role of IgE-dependent basophil activation and FcepsilonRI. | Carboplatin | Fc epsilon receptor Ia | Homo sapiens |
| 2 | To investigate whether IgE-dependent mechanisms, including the overexpression of FcepsilonRI, participate in carboplatin-induced basophil activation, 13 ovarian cancer patients were enrolled: 5 with a history of carboplatin-induced severe hypersensitivity reaction within the past 2 years, and 8 with no such history. | Carboplatin | Fc epsilon receptor Ia | Homo sapiens |
| 3 | To investigate whether IgE-dependent mechanisms, including the overexpression of FcepsilonRI, participate in carboplatin-induced basophil activation, 13 ovarian cancer patients were enrolled: 5 with a history of carboplatin-induced severe hypersensitivity reaction within the past 2 years, and 8 with no such history. | Carboplatin | Fc epsilon receptor Ia | Homo sapiens |
| 4 | In conclusion, an IgE-dependent mechanism incorporating FcepsilonRI overexpression participates in carboplatin-induced severe HR. | Carboplatin | Fc epsilon receptor Ia | Homo sapiens |