Title : Critical role of STAT3 in melanoma metastasis through anoikis resistance.

Pub. Date : 2014 Aug 30

PMID : 25216522






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 STAT3 inhibitors, AG 490 and piplartine (PL) induced anoikis in a concentration-dependent manner in anoikis resistant cells. piplartine signal transducer and activator of transcription 3 Mus musculus
2 Over-expression of STAT3 or treatment with IL-6 not only increased anoikis resistance, but also protected the cancer cells from PL-induced anoikis. piplartine signal transducer and activator of transcription 3 Mus musculus