Title : Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels.

Pub. Date : 2014

PMID : 25210767






1 Functional Relationships(s)
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1 RESULTS: The carriers (N = 27) of a well-defined CYP21A2 haplotype cluster (c5) had significantly elevated levels of cortisol (p = 0.0110), and 17-hydroxyprogesterone (p = 0.0001) after ACTH stimulation, and 11-deoxycortisol after metyrapone administration (p = 0.0017), but the hormone values were in normal ranges. 17-alpha-Hydroxyprogesterone cytochrome P450 family 21 subfamily A member 2 Homo sapiens