Title : Research/review: Insights into the mutation-induced dysfunction of arachidonic acid metabolism from modeling of human CYP2J2.

Pub. Date : 2014

PMID : 25204827






1 Functional Relationships(s)
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Protein Name
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1 Located at the endoplasmic reticulum, CYP2J2 is responsible for epoxidation of endogenous arachidonic acid in cardiac tissue to produce cis-epoxyeicosatrienoic acids (EETs), which have anti-inflammatory and antifibrinolytic properties, and can protect endothelial cells from ischemic or hypoxic injuries. eets cytochrome P450 family 2 subfamily J member 2 Homo sapiens