Title : Evaluation of antitumor effect of zoledronic acid entrapped in folate-linked liposome for targeting to tumor-associated macrophages.

Pub. Date : 2015

PMID : 25203609






1 Functional Relationships(s)
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1 When fluorescent-labeled folic acid was intravenously injected into mice bearing FR-positive human nasopharyngeal tumor KB, and FR-negative human prostate tumor PC-3 and mouse colon adenocarcinoma Colon 26, fluorescence was strongly detected in KB and Colon 26 tumors, and moderately in PC-3 tumor, indicating that folic acid was taken up by TAMs via FRbeta in PC-3 and Colon 26 tumors. Folic Acid folate receptor 2 (fetal) Mus musculus