Title : Matrix metalloproteinase-2 and -14 in p16-positive and -negative HNSCC after exposure To 5-FU and docetaxel In Vitro.

Pub. Date : 2014 Sep

PMID : 25202075






2 Functional Relationships(s)
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1 RESULTS: Docetaxel exposure significantly decreased MMP-14 expression in HNSCC 11A and especially 14C but not in CERV196 apart from an apoptotic process. Docetaxel matrix metallopeptidase 14 Homo sapiens
2 CONCLUSION: Although neither of the applied drugs were selective inhibitors of MMP-expression, surprisingly docetaxel significantly decreased MMP-14 in HNSCC 14C and 11A in this study. Docetaxel matrix metallopeptidase 14 Homo sapiens