Title : Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site.

Pub. Date : 2014 Oct 1

PMID : 25192810






1 Functional Relationships(s)
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1 Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1"" binding site. Benzoic Acid matrix metallopeptidase 13 Bos taurus