Title : Safety, tolerability, and clinical effect of low-dose buprenorphine for treatment-resistant depression in midlife and older adults.

Pub. Date : 2014 Aug

PMID : 25191915






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1 OBJECTIVE: To describe the clinical effect and safety of low-dose buprenorphine, a kappa-opioid receptor antagonist, for treatment-resistant depression (TRD) in midlife and older adults. Buprenorphine opioid receptor kappa 1 Homo sapiens