Title : Hyper-inflammation and skin destruction mediated by rosiglitazone activation of macrophages in IL-6 deficiency.

Pub. Date : 2015 Feb

PMID : 25184961






1 Functional Relationships(s)
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1 IL-6 deficiency when combined with Rosi-mediated upregulation of suppressor of cytokine signaling 3 leads to an altered ratio of nuclear signal transducer and activator of transcription 3/NF-kappaB that allows hyper-induction of inducible nitric oxide synthase (iNOS). Rosiglitazone signal transducer and activator of transcription 3 Homo sapiens