Title : Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscle.

Pub. Date : 2014

PMID : 25180167






3 Functional Relationships(s)
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1 AIMS: Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and both are stimulated by tumor necrosis factor (TNF), suggesting a connection between systems. Sphingolipids tumor necrosis factor Homo sapiens
2 AIMS: Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and both are stimulated by tumor necrosis factor (TNF), suggesting a connection between systems. Sphingolipids tumor necrosis factor Homo sapiens
3 INNOVATION: These findings identify nSMase3 as an intermediate that links TNF receptor activation, sphingolipid signaling, and skeletal muscle oxidant production. Sphingolipids tumor necrosis factor Homo sapiens