Title : Protective effects of scoparone against lipopolysaccharide-induced acute lung injury.

Pub. Date : 2014 Nov

PMID : 25151099






2 Functional Relationships(s)
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1 The results showed that scoparone treatment remarkably attenuated LPS-induced pulmonary edema, histological severities, myeloperoxidase activity, and TNF-alpha, IL-6 and IL-1beta production in vivo. scoparone interleukin 1 beta Mus musculus
2 We also found that scoparone inhibited LPS-induced TLR4 expression, NF-kappaB activation, TNF-alpha, IL-6 and IL-1beta production in alveolar macrophages in vitro. scoparone interleukin 1 beta Mus musculus