Title : Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson's disease: involvement of ERK1/2-Nrf2 signaling pathway.

Pub. Date : 2014 Oct 2

PMID : 25132361






3 Functional Relationships(s)
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1 Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson"s disease: involvement of ERK1/2-Nrf2 signaling pathway. gastrodin mitogen-activated protein kinase 3 Mus musculus
2 SIGNIFICANCE: Gastrodin protects midbrain of MPTP-intoxicated mice against oxidative stress, in part, through interrupting ERK1/2-Nrf2 pathway mechanism, which will give us an insight into the potential of gastrodin in terms of opening up new therapeutic avenues for PD. gastrodin mitogen-activated protein kinase 3 Mus musculus
3 SIGNIFICANCE: Gastrodin protects midbrain of MPTP-intoxicated mice against oxidative stress, in part, through interrupting ERK1/2-Nrf2 pathway mechanism, which will give us an insight into the potential of gastrodin in terms of opening up new therapeutic avenues for PD. gastrodin mitogen-activated protein kinase 3 Mus musculus