Title : Lumisterol is metabolized by CYP11A1: discovery of a new pathway.

Pub. Date : 2014 Oct

PMID : 25130438






2 Functional Relationships(s)
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1 22-Hydroxy-L3 was further metabolized by bovine CYP11A1 to 20,22-dihydroxy-L3. 20,22-dihydroxy-l3 cholesterol side-chain cleavage enzyme, mitochondrial Bos taurus
2 Thus, we have established that L3 is metabolized by CYP11A1 to 22- and 24-hydroxy-L3 and 20,22-dihydroxy-L3 as major products, as well as to pL and other minor products. 20,22-dihydroxy-l3 cholesterol side-chain cleavage enzyme, mitochondrial Bos taurus