Title : Celastrol may have an anti-atherosclerosis effect in a rabbit experimental carotid atherosclerosis model.

Pub. Date : 2014

PMID : 25126165






3 Functional Relationships(s)
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1 The expression of VEGF in the celastrol group was significantly less compared with the model group (P = 0.014), whereas the expression of VEGF in the atorvastatin group and the model group showed no significant differences. celastrol vascular endothelial growth factor A Oryctolagus cuniculus
2 CONCLUSION: Our findings suggest that celastrol effectively reduced the plaque ratio, decreased the serum levels of LDL and downregulated the expression of VEGF, suggesting an anti-AS effect of celastrol. celastrol vascular endothelial growth factor A Oryctolagus cuniculus
3 CONCLUSION: Our findings suggest that celastrol effectively reduced the plaque ratio, decreased the serum levels of LDL and downregulated the expression of VEGF, suggesting an anti-AS effect of celastrol. celastrol vascular endothelial growth factor A Oryctolagus cuniculus