Title : [The mechanism of action of nitrates, 1988 status].

Pub. Date : 1989

PMID : 2511690






1 Functional Relationships(s)
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1 The real clinical importance of nitrates became, however, evident only in the last decade with the discovery of EDRF, the so-called endothelial-derived relaxing factor, an endogenous compound of endothelial origin at least partly consisting of nitrous oxide and therefore, like nitrates, it exerts its effect through the stimulation of cGMP. Nitrous Oxide alpha hemoglobin stabilizing protein Homo sapiens